锌指蛋白12抗体
规格:1mg/1ml
英文名: ZNF12
别名: GIOT 3; GIOT3; Gonadotropin inducible transcription repressor 3; Gonadotropin-inducible ovary transcription repressor 3; HZF11; KOX3; zinc finger protein 11; Zinc finger protein 12; Zinc finger protei
分子量: 58kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZNF12
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核
锌指蛋白12抗体产品介绍:background: This gene is a member of the krueppel C2H2-type zinc-finger protein family and encodes a protein with eight C2H2-type zinc fingers and a KRAB domain. This nuclear protein is involved in developmental control of gene expression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Function: Transcriptional repressor which suppresses activation protein 1 (AP-1)- and serum response element (SRE)-mediated transcriptional activity. Subcellular Location: Nuclear Tissue Specificity: Widely expressed in various ***** tissues and embryonic developmental stages (isoform 3) DISEASE:锌指蛋白12抗体 Shows a relatively higher expression level in the fetal brain and a lower level in *****. The expression level in liver is highest at 16 weeks of development and declines from 16 to 24 weeks and is lower in *****. Expressed strongly in fetal heart on 18 and 24 weeks, but relatively weakly on the other development stage of embryo, and then reaches a higher level in ***** (isoform 3) Similarity: Belongs to the krueppel C2H2-type zinc-锌指蛋白12抗体finger protein family. Contains 15 C2H2-type zinc fingers. Contains 1 KRAB domain. Database links: Entrez Gene: 7559 Human Omim: 194536 Human SwissProt: P17014 Human Unigene: 431471 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
锌指蛋白12抗体研究领域:细胞生物 转录调节因子 锌指蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid