锌指蛋白372抗体
规格：1mg/1ml
英文名： ZDHHC2/ZNF372
别名： DHHC-2; Palmitoyltransferase ZDHHC2; Ream; Rec; Reduced expression associated with metastasis protein; Reduced expression in cancer protein; ZDHC2_HUMAN; Zdhhc2; Zinc finger DHHC domain-containing pro
分子量： 42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZDHHC2/Z
交叉反应：Human, Mouse, Rat, Monkey,
细胞定位：细胞膜
锌指蛋白372抗体产品介绍：background: ZDHHC2 is a 367 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. The ubiquitously expressed ZDHHC2 protein functions as a palmitoyltransferase that uses palmitoyl-CoA and catalyzes the conversion of target proteins, namely GAP-43 and PSD-95, to S-palmitoyl proteins. Defects in the gene encoding ZDHHC2 are found in colorectal cancer and hepatocellular carcinoma, suggesting a role for ZDHHC2 in tumorigenesis. The gene encoding human ZDHHC2 maps to chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies锌指蛋白372抗体. Function: Palmitoyltransferase specific for GAP43 and DLG4/PSD95. Subcellular Location: Membrane. Tissue Specificity: Ubiquitously expressed. Reduced expression in colorectal cancers with liver metastasis. DISEASE: Note=Mutations in ZDHHC2 are found in hepatocellular锌指蛋白372抗体 carcinoma and colorectal cancer. Similarity: Belongs to the DHHC palmitoyltransferase family. Contains 1 DHHC-type zinc finger. Database links: Entrez Gene: 51201 Human Entrez Gene: 70546 Mouse Entrez Gene: 246326 Rat SwissProt: Q9UIJ5 Human SwissProt: P59267 Mouse Unigene: 726197 Human Unigene: 34326 Mouse Unigene: 17310 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白372抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 锌指蛋白 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid