ZDHHC13蛋白抗体
规格：1mg/1ml
英文名： ZDHHC13/HIP14L
别名： DHHC 13; DHHC-13; FLJ10852; FLJ10941; HIP14 like; HIP14 related protein; HIP14-related protein; HIP14L; HIP3RP; Huntingtin interacting protein 14 related protein; Huntingtin interacting protein HIP3RP
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZDHHC13/
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
细胞定位：细胞浆
ZDHHC13蛋白抗体产品介绍：background: ZDHHC13 is a 622 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and six ANK repeats. Expressed as multiple alternatively spliced isoforms, HIP14L functions as a palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and a protein-cyeteine to an S-palmitoyl protein and CoA and, via this catalytic activity, may be involved in the NFⅹB signaling pathway. The gene encoding HIP14L maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: Palmitoyltransferase for HD and GAD2 (By similarity).ZDHHC13蛋白抗体 Mediates Mg(2+) transport. Subcellular Location: Golgi apparatus membrane. Cytoplasmic vesicle membrane. Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles. Similarity: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. ZDHHC13蛋白抗体Contains 6 ANK repeats. Contains 1 DHHC-type zinc finger. Database links: Entrez Gene: 422980 Chicken Entrez Gene: 54503 Human Entrez Gene: 243983 Mouse Entrez Gene: 365252 Rat Entrez Gene: 494107 Zebrafish Omim: 612815 Human SwissProt: Q8IUH4 Human SwissProt: Q9CWU2 Mouse Unigene: 188569 Human Unigene: 279116 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ZDHHC13蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 表观遗传学
储存条件： Store at -20 ∑C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid