ZC3H12C蛋白抗体
规格：1mg/1ml
英文名： ZC3H12C
别名： MCP induced protein 3; MCP-induced protein 3; MCPIP3; Probable ribonuclease ZC3H12C; ZC12C_HUMAN; ZC3H12C; Zinc finger CCCH domain-containing protein 12C.
分子量： 99kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZC3H12C
交叉反应：Human, Mouse, Rat, Horse,
ZC3H12C蛋白抗体细胞定位：
产品介绍：background: ZC3H12C is an 883 amino acid protein that contains one C3H1-type zinc finger domain and belongs to the ZC3H12 family. ZC3H12C is suggested to function as an RNase, and thereby modifies levels of target RNA. Binding magnesium as a cofactor, ZC3H12C has been found to be induced in THP-1 cells when exposed toTNF?or IL-1. ZC3H12C is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA ZC3H12C蛋白抗体breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Function: May function as RNase and regulate the levels of target RNA species. Similarity: Belongs to the ZC3H12 family. Contains 1 C3H1-type zinc finger. Gene ID: 85463 Database links: Entrez ZC3H12C蛋白抗体Gene: 85463 Human Entrez Gene: 244871 Mouse Entrez Gene: 315658 Rat Omim: 615001 Human SwissProt: Q9C0D7 Human SwissProt: Q5DTV4 Mouse Unigene: 376289 Human Unigene: 295686 Mouse Unigene: 390172 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ZC3H12C蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子 表观遗传学
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid