富含亮氨酸重复蛋白51抗体
规格:1mg/1ml
英文名: LRTOMT/LRRC51
别名: COMT2; DFNB63; Leucine rich repeat-containing protein 51; Leucine rich transmembrane and 0-methyltransferase domain containing; LRRC51; LRTOMT1; LRTOMT2; Protein LRTOMT1.
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LRTOMT/L
交叉反应:Human, Mouse, Rat, Dog, hu, mo, rat, dog
细胞定位:细胞浆
富含亮氨酸重复蛋白51抗体产品介绍:background: This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function.富含亮氨酸重复蛋白51抗体 Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012] Subcellular Location: Cytoplasmic Similarity: Contains 3 LRR富含亮氨酸重复蛋白51抗体 (leucine-rich) repeats. Contains 1 LRRCT domain. Gene ID: 220074 Database links: Entrez Gene: 220074 Human Entrez Gene: 69358 Mouse Omim: 612414 Human SwissProt: Q96E66 Human SwissProt: Q9DAK8 Mouse SwissProt: B6CZ61 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含亮氨酸重复蛋白51抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid