富含亮氨酸重复蛋白8D抗体
规格：1mg/1ml
英文名： LRRC8D
别名： FLJ10470; FLJ20403; LRC8D_HUMAN; Leucine rich repeat containing 5; Leucine rich repeat containing 8 family member D; Leucine rich repeat containing protein 8D; LRRC 5; LRRC 8D; LRRC5.
分子量： 98kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LRRC8D
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞膜
富含亮氨酸重复蛋白8D抗体产品介绍：background: LRRC8D contains 12 LRR (leucine-rich) repeats. The function of this protein is unknown. Function: Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8D constitutes a pore-forming subunit or whether it is closely 富含亮氨酸重复蛋白8D抗体associated with the pore (By similarity). Mediates the import of the antibiotic blasticidin-S into cell (PubMed:24782309). Subunit: Heterooligomer; heterooligomerizes with other LRRC8 proteins (LRRC8A, LRRC8B, LRRC8C and/or LRRC8E), possibly to form a heterohexamer. Subcellular Location: Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. 富含亮氨酸重复蛋白8D抗体Note=Mainly localizes in the endoplasmic reticulum Similarity: Belongs to the LRRC8 family. Contains 13 LRR (leucine-rich) repeats. Gene ID: 55144 Database links: Entrez Gene: 55144 Human SwissProt: Q7L1W4 Human Unigene: 482087 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含亮氨酸重复蛋白8D抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid