低密度脂蛋白受体相关蛋白5+6抗体
规格：1mg/1ml
英文名： LRP5 + LRP6
别名： BMND 1; BMND1; EVR 1; EVR 4; EVR1; EVR4; FLJ90062; FLJ90421; HBM; LDL Receptor Related Protein 5 + 6; Low density lipoprotein receptor related protein 5; Low density lipoprotein receptor related prote
分子量： 176kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LRP5 + L
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Sheep,
细胞定位：细胞膜
低密度脂蛋白受体相关蛋白5+6抗体产品介绍：background: LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization. Subcellular Location: Membrane; single-pass type I membrane protein Similarity:低密度脂蛋白受体相关蛋白5+6抗体 Belongs to the LDLR family. Contains 4 EGF-like domains. Contains 3 LDL-receptor class A domains. Contains 20 LDL-receptor class B repeats. Gene ID: 4040 4041 Database links: Entrez Gene: 4040 Human Entrez Gene: 4041 Human Entrez Gene: 16973 Mouse Entrez Gene: 16974 Mouse Omim: 603506 Human Omim: 603507 Human SwissProt: O75197 Human SwissProt: O75581 Human SwissProt:低密度脂蛋白受体相关蛋白5+6抗体 O88572 Mouse SwissProt: Q91VN0 Mouse Unigene: 45360 Human Unigene: 584775 Human Unigene: 6347 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
低密度脂蛋白受体相关蛋白5+6抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 细胞膜受体 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid