低密度脂蛋白受体相关蛋白3抗体
规格：1mg/1ml
英文名： LRP3
别名： 105 kDa low-density lipoprotein receptor-related protein; hLRp105; Low density lipoprotein receptor related protein 3; Low-density lipoprotein receptor-related protein 3; LRP-3; Lrp3; LRP3_HUMAN.
分子量： 79kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LRP3
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位：细胞膜
低密度脂蛋白受体相关蛋白3抗体产品介绍：background: Low-density lipoprotein receptor-related protein 3 (LRP3) is a 770 amino acid protein that contains two CUB domains and four LDL-receptor class A domains. LRP3 is widely expressed with highest expression in skeletal muscle and ovary and lowest expression in testis, colon and leukocytes. LRP3 is potentially a membrane receptor involved in the internalization of lipophilic molecules and/or signal transduction. Function: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro. Subcellular Location: Membrane. Membrane > coated pit.Target information above from: UniProt accession O75074 The UniProt Consortium The Universal低密度脂蛋白受体相关蛋白3抗体 Protein Resource (UniProt) in 2010 Nucleic Acids Res. 38:D142-D148 (2010) . Tissue Specificity: Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte. Similarity: Belongs to the LDLR family. Contains 2 CUB domains. Contains 4 LDL-receptor class A 低密度脂蛋白受体相关蛋白3抗体domains. Gene ID: 4037 Database links: Entrez Gene: 4037 Human Entrez Gene: 435965 Mouse Entrez Gene: 89787 Rat Omim: 603159 Human SwissProt: O75074 Human SwissProt: O88204 Rat Unigene: 515340 Human Unigene: 273631 Mouse Unigene: 145216 Rat Unigene: 87059 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet 低密度脂蛋白受体相关蛋白3抗体tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞膜受体 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid