低密度脂蛋白相关蛋白2结合蛋白抗体
规格：1mg/1ml
英文名： LRP2BP
别名： DKFZp761O0113; FLJ44965; KIAA1325; LR2BP_HUMAN; LRP2 binding protein; LRP2-binding protein; Lrp2bp; Megalin binding protein; Megalin-binding protein; MegBP.
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LRP2BP
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
低密度脂蛋白相关蛋白2结合蛋白抗体产品介绍：background: LRP2BP is a 347 amino acid protein that contains one TPR repeat and six Sel1-like repeats. Localized to the plasma membrane and throughout the cytoplasm, LRP2BP interacts with megalin (also known as LRP2) and, via this interaction, is thought to regulate megalin function. Specifically, LRP2BP acts as a scaffold protein that, through its TPR motifs, assists in the sequestration and/or the release of transcription factors that influence megalin’s affects on endocytosis and hormone release. LRP2BP is expressed in colon, testis, small intestine and blood leukocytes, as well as in pancreatic adenocarcinoma cells, suggesting a possible role for 低密度脂蛋白相关蛋白2结合蛋白抗体LRP2BP in carcinogenesis. Two isoforms of LRP2BP exist due to alternative splicing events. Function: May act as an adapter that regulates LRP2 function. Subcellular Location: Cytoplasm. Detected in a vesicular staining pattern close to the plasma membrane and throughout the cytoplasm. Similarity: Contains 6 Sel1-like repeats. Contains 1 TPR repeat. Gene ID: 55805 Database links: Entrez Gene: 55805 低密度脂蛋白相关蛋白2结合蛋白抗体Human Entrez Gene: 67620 Mouse Entrez Gene: 290753 Rat Entrez Gene: 100073340 Zebrafish SwissProt: Q9P2M1 Human SwissProt: Q9D4C6 Mouse SwissProt: Q569C2 Rat SwissProt: A5PLI4 Zebrafish Unigene: 558513 Human Unigene: 383914 Mouse Unigene: 108662 Rat Unigene: 94415 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
低密度脂蛋白相关蛋白2结合蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid