T**细胞转运蛋白1抗体
规格：1mg/1ml
英文名： LMO1
别名： Cysteine rich protein TTG 1; Cysteine rich protein TTG1; LIM domain only 1; LIM domain only protein 1; LMO 1; MGC116692; RBTN 1; RBTN1; RHOM 1; RHOM1; Rhombotin 1; Rhombotin1; T cell translocation pro
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LMO1
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Zebrafish, Guinea Pig, Monkey, Cat, Spider Monkey
细胞定位：细胞核
T**细胞转运蛋白1抗体产品介绍：background: This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeqT**细胞转运蛋白1抗体, Jul 2012] Function: May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors. Subcellular Location: Nuclear Tissue Specificity: Expressed mainly in the central nervous. Low level of expression in other tissues including thymus. DISEASE: A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia T**细胞转运蛋白1抗体(T-ALL). Translocation t(11,14)(p15;q11) with TCRD. Similarity: Contains 2 LIM zinc-binding domains. Database links: Entrez Gene: 27152 Cow Entrez Gene: 4004 Human Entrez Gene: 109594 Mouse Entrez Gene: 245979 Rat Entrez Gene: 280646 Zebrafish Omim: 186921 Human SwissProt: Q0P5B3 Cow SwissProt: P25800 Human SwissProt: Q924W9 Mouse SwissProt: Q8JFQ2 Zebrafish Unigene: 654426 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
T**细胞转运蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转运蛋白 **细胞 t-**细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid