LIMD2蛋白抗体
规格:1mg/1ml
英文名: LIMD2
别名: LIM domain containing 2; MGC10986.
分子量: 14kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LIMD2
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞浆
LIMD2蛋白抗体产品介绍:background: Limd2 (LIM domain-containing protein 2) is a 127 amino acid protein that contains one LIM zinc-binding domain. The gene encoding Limd2 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or LIMD2蛋白抗体loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Function: LIMD2 contains 1 LIM zinc-binding domain. Similarity: Contains 1 LIM zinc-binding domain. Gene ID: LIMD2蛋白抗体80774 Database links: Entrez Gene: 80774 Human SwissProt: Q9BT23 Human Unigene: 591166 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
LIMD2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid