膀胱癌和乳腺癌过表达基因抗体
规格：1mg/1ml
英文名： LENG4
别名： 1-acylglycerophosphatidylinositol O-acyltransferase; Bladder and breast carcinoma-overexpressed gene 1 protein; h-mboa-7; Leukocyte receptor cluster member 4; LPIAT; LPLAT 7; Lyso-PI acyltransferase;
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
免疫原：KLH conjugated synthetic peptide derived from human LENG4
交叉反应：Human, Mouse, Rat, Dog, Cow,
细胞定位：细胞膜
膀胱癌和乳腺癌过表达基因抗体产品介绍：background: This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009] Function: Acyltransferase which mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor. Lysophospholipid acyltransferases膀胱癌和乳腺癌过表达基因抗体 (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. Subcellular Location: Membrane. Tissue Specificity: Overexpressed in metastatic breast and bladder carcinomas relative to normal breast epithelium 膀胱癌和乳腺癌过表达基因抗体and urothelium. Similarity: Belongs to the membrane-bound acyltransferase family. Gene ID: 79143 Database links: Entrez Gene: 79143 Human Entrez Gene: 77582 Mouse SwissProt: Q96N66 Human SwissProt: Q8CHK3 Mouse Unigene: 467279 Human Unigene: 482149 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膀胱癌和乳腺癌过表达基因抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 免疫学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid