神经胰蛋白酶抗体
规格：1mg/1ml
英文名： Neurotrypsin
别名： BSSP 3; BSSP3; Leydin; MGC12722; MOTOPSIN; MRT1; NETR_HUMAN; Neurotrypsin; protease, serine, 12 (neurotrypsin, motopsin); Prss12; Serine protease 12.
分子量： 95kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Neurotry
交叉反应：Human,
细胞定位：分泌型蛋白
神经胰蛋白酶抗体产品介绍：background: This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). [provided by RefSeq, Jul 2010] Function: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Subcellular Location: Secreted. Tissue Specificity: Brain and Leydig cells of the testis. DISEASE: Defects in PRSS12 are the cause of mental retardation autosomal recessive type 1 (MRT1) [MIM:249500]. Mental retardation is a 神经胰蛋白酶抗体mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Similarity: Belongs to the peptidase S1 family. Contains 1 kringle domain. Contains 1 peptidase S1 domain. Contains 4 SRCR domains. Gene ID: 8492神经胰蛋白酶抗体 Database links: Entrez Gene: 8492 Human Entrez Gene: 19142 Mouse Entrez Gene: 85266 Rat SwissProt: P56730 Human SwissProt: O08762 Mouse SwissProt: Q99JC8 Rat Unigene: 445857 Human Unigene: 9431 Mouse Unigene: 86653 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经胰蛋白酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid