配体依赖核受体共抑制因子抗体
规格：1mg/1ml
英文名： MLR2
别名： A630025C20RIK; FLJ38026; KIAA1795; LCoR; Lcor; LCOR_HUMAN; Ligand dependent corepressor; Ligand dependent nuclear receptor corepressor; Ligand-dependent corepressor; Mblk1 related protein 2; Mblk1-rel
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MLR2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
配体依赖核受体共抑制因子抗体产品介绍：background: LCOR is a transcriptional corepressor widely expressed in fetal and ***** tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008] Function: May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription 配体依赖核受体共抑制因子抗体activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Similarity: Contains 1 HTH 配体依赖核受体共抑制因子抗体psq-type DNA-binding domain. Gene ID: 84458 Database links: Entrez Gene: 84458 Human Entrez Gene: 212391 Mouse Entrez Gene: 365462 Rat Omim: 607698 Human SwissProt: Q96JN0 Human SwissProt: Q6ZPI3 Mouse Unigene: 729136 Human Unigene: 398778 Mouse Unigene: 422910 Mouse Unigene: 459119 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
配体依赖核受体共抑制因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid