干扰素调节因子9抗体
规格：1mg/1ml
英文名： IRF9/ISGF3
别名： IFN alpha responsive transcription factor subunit; IFN-alpha-responsive transcription factor subunit; Interferon regulatory factor 9; interferon stimulated transcription factor 3; Interferon-stimulate
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IRF9/ISG
交叉反应：Human,
细胞定位：细胞核 细胞浆
干扰素调节因子9抗体产品介绍：background: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon干扰素调节因子9抗体 stimulated genes, which drive the cell in an antiviral state. Subcellular Location: Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta. Similarity: Belongs to the IRF family. Contains 1 IRF tryptophan pentad repeat DNA-binding domain. Gene ID: 10379 Database links: Entrez Gene: 10379 Human Entrez Gene: 16391 Mouse Entrez Gene: 305896 Rat Omim: 147574 Human SwissProt: Q00978 干扰素调节因子9抗体Human SwissProt: Q61179 Mouse Unigene: 1706 Human Unigene: 2032 Mouse Unigene: 163277 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
干扰素调节因子9抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid