Toll蛋白相互作用蛋白抗体
规格：1mg/1ml
英文名： Tollip
别名： Adapter protein; FLJ33531; IL 1RAcPIP; IL1RAcPIP; TOLIP; TOLIP_HUMAN; Toll interacting protein; Toll-interacting protein; tollip.
分子量： 30kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Tollip
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Xenopus laevis
细胞定位：细胞膜
Toll蛋白相互作用蛋白抗体产品介绍：background: This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. [provided by RefSeq, Aug 2011] Function: Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. Subcellular Location: Cytoplasm. Post-translational modifications: Phosphorylated by IRAK1 upon stimulation by IL-1 orToll蛋白相互作用蛋白抗体 microbial products. Similarity: Belongs to the tollip family. Contains 1 C2 domain. Contains 1 CUE domain. Gene ID: 54472 Database links: Entrez Gene: 54472 Human Entrez Gene: 423099 Chicken Entrez Gene: 539480 Cow Entrez Gene: 54473 Mouse Entrez Gene: 361677 Rat Entrez Gene: 336876 Zebrafish Omim: 606277 Human SwissProt: Q5ZK05 Chicken SwissProt: Q2LGB5 Cow SwissProt: Q9H0E2Toll蛋白相互作用蛋白抗体 Human SwissProt: Q9QZ06 Mouse SwissProt: A2RUW1 Rat SwissProt: Q7ZV43 Zebrafish Unigene: 368527 Human Unigene: 103551 Mouse Unigene: 137040 Rat Unigene: 79855 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Toll蛋白相互作用蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid