白细胞介素28受体α抗体
规格：1mg/1ml
英文名： IL28 Receptor alpha
别名： Class II cytokine receptor CRF2/12; CRF2-12; CRF2/12; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; IFN lambda R1; IFN-lambda receptor 1; IFNLR; IFNLR1; IL-28 receptor su
分子量： 56kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IL28 Rec
交叉反应：Human,
细胞定位：细胞膜
白细胞介素28受体α抗体产品介绍：background: The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by 白细胞介素28受体α抗体RefSeq, Jul 2008] Function: IL28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain. Subcellular Location: Membrane; Single-pass type I membrane protein Gene ID: 163702白细胞介素28受体α抗体 Database links: Entrez Gene: 163702 Human Entrez Gene: 362628 Rat Omim: 607404 Human SwissProt: Q8IU57 Human Unigene: 221375 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白细胞介素28受体α抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid