白细胞介素12p70抗体
规格:1mg/1ml
英文名: IL12 p70
别名: CLMF p35; CLMF p40; Cytotoxic lymphocyte maturation factor 35 kDa subunit; Cytotoxic lymphocyte maturation factor 40 kDa subunit; IL12A; IL12B; Interleukin 12 alpha chain; Interleukin-12 beta chain; N
分子量: 25 ,37kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IL12 p70
交叉反应:Human, Dog,
细胞定位:分泌型蛋白
白细胞介素12p70抗体产品介绍:background: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are 白细胞介素12p70抗体mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008] Function: IL12 p70 is a disulfide bonded heterodimer of the IL12 40 kDa and 35 kDa subunits. Subunit: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12. Subcellular 白细胞介素12p70抗体Location: Secreted Similarity: Belongs to the IL-6 superfamily. Gene ID: 3592 Database links: Entrez Gene: 3592 Human Entrez Gene: 3593 Human Omim: 161560 Human Omim: 161561 Human SwissProt: P29459 Human SwissProt: P29460 Human Unigene: 673 Human Unigene: 674 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白细胞介素12p70抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid