钙蛋白酶5抗体
规格：1mg/1ml
英文名： HTRA3/Calpain 5
别名： Calpain 5; Calpn 5; CAPN5; EC 3.4.21.; High temperature requirement factor A3; High-temperature requirement factor A3; HtrA serine peptidase 3; HTRA3; HTRA3_HUMAN; Pregnancy related serine protease; P
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HTRA3/Ca
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：分泌型蛋白
钙蛋白酶5抗体产品介绍：background: HtrA3 is a 453 amino acid secreted protein that contains one PDZ domain, one Kazal-like domain and one IGFBP N-terminal domain. Widely expressed with particularly high expression in ovary, heart, placenta and bladder, HtrA3 functions as a probable serine protease that is thought to play an important role in placental development. HtrA3 is downregulated in ovarian tumors, suggesting an alternative role in tumor suppression. HtrA3 exists as two alternatively spliced isoforms, designated short and long. The gene encoding HtrA3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the钙蛋白酶5抗体 genome with no protein encoding genes) of all of the human chromosomes. Function: Probable serine protease. Subcellular Location: Secreted. Tissue Specificity: Widely expressed, with highest levels in both ***** and fetal heart, ovary, uterus placenta, and bladder. Isoform 1 is predominant in heart and skeletal muscle, whereas isoform 2 is predominant in placenta and kidney. Similarity: Belongs to the peptidase 钙蛋白酶5抗体S1B family. Contains 1 IGFBP N-terminal domain. Contains 1 Kazal-like domain. Contains 1 PDZ (DHR) domain. Gene ID: 94031 Database links: Entrez Gene: 94031 Human Entrez Gene: 360959 Rat Omim: 608785 Human SwissProt: P83110 Human SwissProt: D3ZA76 Rat Unigene: 479119 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙蛋白酶5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid