GSK3β相互作用蛋白抗体
规格：1mg/1ml
英文名： HSPC210/GSK3beta interaction protein
别名： C14ORF129; Chromosome 14 open reading frame 129; GSK3-beta interaction protein; GSK3beta interaction protein; GSKIP; GSKIP; GSKIP_HUMAN; MGC4945; UPF0279.
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HSPC210/
交叉反应：Human, Mouse, Rat, Cynomolgus Monkey
细胞定位：细胞浆
GSK3β相互作用蛋白抗体产品介绍：background: This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced GSK3β相互作用蛋白抗体transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012] Subcellular Location: Cytoplasm. Tissue Specificity: Detected in heart, brain, placenta, liver, skeletal muscle, kidney, testis, lung and pancreas. Similarity: BelongsGSK3β相互作用蛋白抗体 to the UPF0279 family. Gene ID: 51527 Database links: Entrez Gene: 51527 Human Entrez Gene: 66787 Mouse Entrez Gene: 362778 Rat SwissProt: Q9P0R6 Human SwissProt: Q8BGR8 Mouse SwissProt: Q5PPI3 Rat Unigene: 728153 Human Unigene: 248019 Mouse Unigene: 3701 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GSK3β相互作用蛋白抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid