肝细胞核因子6抗体
规格：1mg/1ml
英文名： HNF6
别名： hepatocyte nuclear factor 6 alpha; Hepatocyte nuclear factor 6; HNF 6; HNF-6; HNF6_HUMAN; HNF6A; One cut domain family member 1; One cut homeobox 1; Onecut1.
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HNF6
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：细胞核
肝细胞核因子6抗体产品介绍：background: This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] Function: Transcriptional activator. Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and 肝细胞核因子6抗体TTR. Important for liver genes transcription. Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in liver; lower expression in testis and skin. Similarity: Belongs to the CUT homeobox family. Contains 1 CUT DNA-binding domain. Contains 1 homeobox DNA-binding domain. Gene ID: 3175 Database links: Entrez Gene: 3175 Human Entrez Gene: 15379 Mouse Entrez Gene: 25231 Rat Omim: 604164 肝细胞核因子6抗体Human SwissProt: Q9UBC0 Human SwissProt: O08755 Mouse SwissProt: P70512 Rat Unigene: 658573 Human Unigene: 303355 Mouse Unigene: 48812 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肝细胞核因子6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 转录调节因子 新陈代谢 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid