肝细胞核因子4γ抗体
规格：1mg/1ml
英文名： HNF4 gamma
别名： Hepatocyte nuclear factor 4 gamma; Hepatocyte nuclear factor 4-gamma; HNF 4 gamma; HNF-4-gamma; HNF4G; HNF4G_HUMAN; NR2A2; NR2A3; Nuclear receptor subfamily 2 group A member 2.
分子量： 46kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HNF4 gam
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, Cat,
细胞定位：细胞核
肝细胞核因子4γ抗体产品介绍：background: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] Function: Transcription factor. Has a lower transcription activation potential than HNF4-alpha. Subcellular Location: Nucleus. Tissue Specificity: Expressed in pancreas, kidney,肝细胞核因子4γ抗体 small intestine and testis. Weakly expressed in colon. Not expressed in liver, skeletal muscle, lung, placenta, brain, heart, peripheral blood, ovary, prostate, thymus and spleen. Similarity: Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear 肝细胞核因子4γ抗体receptor DNA-binding domain. Gene ID: 3174 Database links: Entrez Gene: 3174 Human Entrez Gene: 404168 Cow Entrez Gene: 100050783 Horse Entrez Gene: 30942 Mouse Entrez Gene: 100153753 Pig Entrez Gene: 365744 Rat Omim: 605966 Human SwissProt: Q14541 Human SwissProt: Q9WUU6 Mouse Unigene: 241529 Human Unigene: 330897 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肝细胞核因子4γ抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 糖尿病 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid