HMGCLL1蛋白抗体
规格：1mg/1ml
英文名： HMGCLL1
别名： 3 hydroxymethyl 3 methylglutaryl CoA lyase like protein 1; 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase like 1; Probable 3 hydroxymethyl 3 methylglutaryl CoA lyase 2.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HMGCLL1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞浆
HMGCLL1蛋白抗体产品介绍：background: The 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1 (HMGCLL1) is a 370 amino acid protein that belongs to the HMG-CoA lyase family and is involved in the catabolism of branched amino acids, such as leucine and isoleucine. The gene encoding HMGCLL1 maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity HMGCLL1蛋白抗体complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Function: HMGCLL1 is involved in the catabolism of branched amino acids such as leucine.HMGCLL1蛋白抗体 Similarity: Belongs to the HMG-CoA lyase family. Gene ID: 54511 Database links: Entrez Gene: 54511 Human Entrez Gene: 208982 Mouse Entrez Gene: 367112 Rat SwissProt: Q8TB92 Human SwissProt: Q8JZS7 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
HMGCLL1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid