HMBOX1蛋白抗体
规格：1mg/1ml
英文名： HMBOX1
别名： FLJ21616; HMBOX1; HMBOX1A; HMBX1_HUMAN; HNF1LA; homeobox containing 1; Homeobox containing protein 1; Homeobox-containing protein 1; homeobox-containing protein PBHNF; PBHNF.
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HMBOX1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep,
细胞定位：细胞核 细胞浆
HMBOX1蛋白抗体产品介绍：background: HMBOX1 is a 420 amino acid nuclear protein that contains one homeobox DNA-binding domain and is thought to function as a putative transcription factor. HMBOX1 is expressed as three alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8. Function: Transcription factor. Isoform 1 acts as a transcriptional repressor. Isoform 4 has very low activity as a transcriptional repressor. HMBOX1蛋白抗体Subcellular Location: Nucleus. Cytoplasm. Predominantly detected in cytoplasm. Tissue Specificity: Ubiquitous. Detected in pancreas, brain, spleen, placenta, prostate, thymus, liver, heart, bone marrow, skeletal muscle, stomach, uterus, testis, kidney, ovary, HMBOX1蛋白抗体and colon. Similarity: Contains 1 homeobox DNA-binding domain. Gene ID: 79618 Database links: Entrez Gene: 79618 Human Entrez Gene: 219150 Mouse SwissProt: Q6NT76 Human SwissProt: Q8BJA3 Mouse Unigene: 591836 Human Unigene: 344074 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
HMBOX1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid