白血病抑制因子抗体
规格：1mg/1ml
英文名： HLF
别名： Hepatic leukemia factor; Hlf; HLF/E2A FUSION GENE; HLF_HUMAN.
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HLF
交叉反应：Human, Mouse, Rat, Cow, Horse,
细胞定位：细胞核
白血病抑制因子抗体产品介绍：background: This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] Function: Highly expressed in liver; lower levels in lung and kidney. Subcellular Location:白血病抑制因子抗体 Nucleus. DISEASE: Note=A chromosomal aberration involving HLF is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Translocation t(17;19)(q22;p13.3) with TCF3. Similarity: Belongs to the bZIP family. PAR subfamily. 白血病抑制因子抗体Contains 1 bZIP domain. Gene ID: 3131 Database links: Entrez Gene: 3131 Human Entrez Gene: 217082 Mouse Entrez Gene: 363667 Rat Omim: 142385 Human SwissProt: Q16534 Human SwissProt: Q8BW74 Mouse SwissProt: Q64709 Rat Unigene: 196952 Human Unigene: 158903 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白血病抑制因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid