神经细胞NB3特定蛋白抗体
规格:1mg/1ml
英文名: Contactin 6
别名: CNTN 6; CNTN6; CNTN6_HUMAN; Contactin 6 precursor; Contactin-6; Contactin6; hNB 3; hNB-3; hNB3; MGC133256; NB 3; NB3; Neural adhesion molecule; Neural recognition molecule NB 3; Neural recognition mol
分子量: 109kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NB3
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞膜
神经细胞NB3特定蛋白抗体产品介绍:background: Contactin 6 is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein which functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Function: Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination. Subunit: Belongs to the immunoglobulin superfamily. Contactin family. Contains 4 fibronectin type-III domains. Contains 6 Ig-like C2-type (immunoglobulin-like) domains神经细胞NB3特定蛋白抗体. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor (By similarity). Tissue Specificity: Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord. Similarity: Belongs to the immunoglobulin superfamily. Contactin family. Contains 4 fibronectin type-III domains. 神经细胞NB3特定蛋白抗体Contains 6 Ig-like C2-type (immunoglobulin-like) domains. Gene ID: 27255 Database links: Entrez Gene: 27255 Human Entrez Gene: 53870 Mouse Entrez Gene: 27256 Rat Omim: 607220 Human SwissProt: Q9UQ52 Human SwissProt: Q9JMB8 Mouse SwissProt: P97528 Rat Unigene: 387300 Human Unigene: 321671 Mouse Unigene: 10644 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用:神经细胞NB3特定蛋白抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid