粘蛋白17抗体
规格：1mg/1ml
英文名： MUC17
别名： Membrane mucin MUC17; MUC-17; MUC-3; MUC17; MUC17_HUMAN; Mucin 17, cell surface associated; Mucin-17; Secreted mucin MUC17; Small intestinal mucin MUC3; Small intestinal mucin-3.
分子量： 449kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MUC17
交叉反应：Human,
细胞定位：细胞膜 分泌型蛋白
粘蛋白17抗体产品介绍：background: Membrane mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their apical/basal polarization.[supplied by OMIM, Apr 2004] Function: Probably plays a role in maintaining homeostasis on mucosal surfaces. Subcellular Location: Cell membrane and Secreted. Cell membrane. Tissue Specificity: Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in粘蛋白17抗体 pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers. Post-translational modifications: Probably cleaved within the SEA domain. N-glycosylated. Contains high mannose and 粘蛋白17抗体complex-type glycans. The forms containing the complex type glycans localize to the cell surface. Not O-glycosylated. Similarity: Contains 1 EGF-like domain. Contains 1 SEA domain. Gene ID: 140453 Database links: Entrez Gene: 140453 Human SwissProt: Q685J3 Human Unigene: 271819 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
粘蛋白17抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid