线粒体转录终止因子2抗体
规格：1mg/1ml
英文名： MTERFD2
别名： FLJ16261; HSPC096; MGC61716; MTER2_HUMAN; MTERF domain containing 2; mTERF domain-containing protein 2; Mterfd2; OTTHUMP00000200479; OTTHUMP00000200519.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MTERFD2
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
产品介绍：background: Members of the MTERF (mitochondrial transcription termination factor) family, including MTERF, MTERFD1, MTERFD2 and 线粒体转录终止因子2抗体MTERFD3, are mitochondrial proteins that are that thought to be transcription termination factors. MTERF (mitochondrial transcription termination factor 1) is composed of three leucine zippers that form a three-stranded coiled-coil that binds to DNA. It is suggested that only the phosphorylated form of MTERF has transcription termination activity. MTERFD1 (MTERF domain containing 1) may play a role as a mitochondrial transcription regulator and is expressed as two isoforms produced by alternative splicing. MTERFD2 is a 381 amino acid protein that is encoded by a gene located on human chromosome 2q37.3. MTERFD3 is believed to be involved in cell cycle regulation and线粒体转录终止因子2抗体cell growth by modulating mitochondrial transcription. MTERFD3 is expressed in heart, skeletal muscle, pancreas and liver. Function: Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S). Subunit: Heterodimer with NSUN4; this interaction may be required for线粒体转录终止因子2抗体 NSUN4 recruitment to the mitochondrial large ribosomal subunit. Subcellular Location: Mitochondrion Similarity: Belongs to the mTERF family. Gene ID: 130916 Database links: Entrez Gene: 130916 Human Entrez Gene: 69821 Mouse Entrez Gene: 363289 Rat SwissProt: Q7Z6M4 Human SwissProt: Q8BVN4 Mouse SwissProt: Q4G078 Rat Unigene: 159556 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体转录终止因子2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞周期蛋白 转录调节因子 细胞分化 线粒体 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid