MSH5蛋白抗体
规格：1mg/1ml
英文名： MSH5
别名： DKFZp434C1615; G7; hMSH5; MGC2939; MSH 5; MSH5; MSH5_HUMAN; mutS (E. coli) homolog 5; mutS homolog 5; mutS homolog 5 (E. coli); MutS protein homolog 5; MutSH5; NG23; OTTHUMP00000029187; OTTHUMP0000002
分子量： 93kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MSH5
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Xenopus laevis,
细胞定位：
MSH5蛋白抗体产品介绍：background: This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011]MSH5蛋白抗体 Function: Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis. Subunit: Heterooligomer of MSH4 and MSH5. Interacts with HJURP. Tissue Specificity: Ubiquitous, but highly expressed in testis, and thymus. Similarity: Belongs to the DNA mismatch repair mutS family. Gene ID: 4439 Database links: Entrez Gene: 100139295 Cow Entrez Gene: 474848 Dog Entrez Gene: MSH5蛋白抗体100050672 Horse Entrez Gene: 4439 Human Entrez Gene: 715494 Monkey Entrez Gene: 17687 Mouse Entrez Gene: 100270818 Pig Entrez Gene: 294252 Rat Omim: 603382 Human SwissProt: O43196 Human SwissProt: Q9QUM7 Mouse SwissProt: Q6MG62 Rat Unigene: 647011 Human Unigene: 24192 Mouse Unigene: 44043 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
MSH5蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid