磷酸化肌球蛋白调节多肽9抗体
规格:1mg/1ml
英文名: phospho-MYL9 (Thr19 + Ser20)
别名: MYL9 (phospho T19 + S20); p-MLC(Thr19 + Ser20); phospho-MLC(Thr19 + Ser20); p-Myosin light chain(Thr19 + Ser20); MYL9_HUMAN; Myosin regulatory light polypeptide 9; 20 kDa myosin light chain; LC20; MLC
分子量: 20kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Danio
细胞定位:细胞膜
磷酸化肌球蛋白调节多肽9抗体产品介绍:Function: Myosin light chain (MLC) is a subunit of the conventional myosins (e.g. myosin II). In smooth muscle and non-muscle cells conventional myosins mediate a wide variety of contractile events including cytokinesis, cell motility, and smooth muscle contraction. MLC is phosphorylated by multiple serine-threonine kinases such as Rho-kinase and PAK, however myosin light chain kinase (MLCK) acts as the primary kinase. Contractile activity of conventional myosins is regulated by phosphorylation of MLC on several residues. Subunit: Myosin is an hexamer of 2 heavy chains and 4 light chains. Tissue Specificity: Smooth muscle tissues and in some, but not all,磷酸化肌球蛋白调节多肽9抗体 nonmuscle cells. Post-translational modifications: Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge (By similarity). Similarity: Contains 3 EF-hand domains. Gene ID: 10398 Database links: Entrez Gene: 10398 Human Entrez Gene: 85366 Human Entrez Gene: 228785 Mouse Entrez Gene: 98932 Mouse Entrez Gene: 117558 Rat Entrez Gene: 296313 Rat Omim:磷酸化肌球蛋白调节多肽9抗体 606566 Human Omim: 609905 Human SwissProt: P20689 Human SwissProt: P24844 Human SwissProt: Q8VCR8 Mouse SwissProt: Q9CQ19 Mouse SwissProt: P20689 Rat SwissProt: Q64122 Rat Unigene: 504687 Human Unigene: 271770 Mouse Unigene: 228729 Rat Unigene: 6870 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化肌球蛋白调节多肽9抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 信号转导 干细胞 细胞骨架 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid