线粒体核糖体蛋白L41抗体
规格：1mg/1ml
英文名： MRPL41
别名： 39S ribosomal protein L27 homolog; 39S ribosomal protein L41; 39S ribosomal protein L41 mitochondrial; Bcl-2-interacting mitochondrial ribosomal protein L41; BMRP; Cell proliferation-inducing gene 3 p
分子量： 15kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MRPL41
交叉反应：Human, Mouse, Rat, Chicken, Dog,
细胞定位：细胞浆 线粒体
线粒体核糖体蛋白L41抗体产品介绍：background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family. [provided by RefSeq, Jul 2008] Function: 线粒体核糖体蛋白L41抗体Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. Subcellular Location: Mitochondrion. Tissue Specificity: Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level). Similarity: Belongs to the线粒体核糖体蛋白L41抗体 ribosomal protein L41 family. Gene ID: 64975 Database links: Entrez Gene: 64975 Human Entrez Gene: 107733 Mouse Entrez Gene: 296551 Rat Omim: 611846 Human SwissProt: Q8IXM3 Human SwissProt: Q9CQN7 Mouse SwissProt: Q5BJX1 Rat Unigene: 44017 Human Unigene: 23010 Mouse Unigene: 92811 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体核糖体蛋白L41抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 转录调节因子 线粒体 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid