MRGPRX4蛋白抗体
规格：1mg/1ml
英文名： MRGPRX4
别名： G protein coupled receptor MRGX4; G protein coupled receptor SNSR5; G protein coupled receptor SNSR6; GPCR; Mas related G protein coupled receptor member X4; Mas related G protein coupled-receptor fam
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MRGPRX4
交叉反应：Human,
细胞定位：细胞膜
MRGPRX4蛋白抗体产品介绍：background: Mas-related G protein-coupled receptor member X1 (MRGX) is a sensory neuron-specific G protein-coupled receptor that is involved in the function of nociceptive neurons. This integral membrane protein may also regulate nociceptor development and/or the sensation or modulation of pain. There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G?q- and G?i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G?q-regulated pathways. G?q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in MRGPRX4蛋白抗体a subset of small dorsal root and trigeminal sensory neurons. Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Subcellular Location: Cell membrane. Tissue Specificity: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. MRGPRX4蛋白抗体Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. Gene ID: 117196 Database links: Entrez Gene: 117196 Human Omim: 607230 Human SwissProt: Q96LA9 Human Unigene:MRGPRX4蛋白抗体 632138 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid