抑制素A/Inhibin βA抗体
规格：1mg/1ml
英文名： Inhibin beta A
别名： Activin A; Activin beta A chain; Activin beta-A chain; ActivinA; EDF; Erythroid differentiation factor; Erythroid differentiation protein; INHBA; INHBA_HUMAN; Inhibin beta A chain.
分子量： 13/45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Inhibin
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
抑制素A/Inhibin βA抗体产品介绍：background: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also抑制素A/Inhibin βA抗体 joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome Subunit: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3. Subcellular抑制素A/Inhibin βA抗体 Location: Secreted. Similarity: Belongs to the TGF-beta family. Gene ID: 3624 Database links: Entrez Gene: 3624 Human Entrez Gene: 29200 Rat Omim: 147290 Human SwissProt: P08476 Human SwissProt: P18331 Rat Unigene: 583348 Human Unigene: 9874 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
抑制素A/Inhibin βA抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid