组织相容性复合物相关蛋白MR1抗体
规格：1mg/1ml
英文名： MR1
别名： Class I histocompatibility antigen like protein; HLALS; Major histocompatibility complex class I like sequence; Major histocompatibility complex class I related; Major histocompatibility complex class
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MR1
交叉反应：Human, Mouse, Rat,
细胞定位：
组织相容性复合物相关蛋白MR1抗体产品介绍：background: MR1 is a 341 amino acid single-pass membrane protein that localizes to the endoplasmic reticulum, as well as to the extracellular side of the cell membrane, and contains one Ig-like C1-type domain. Expressed ubiquitously, MR1 exists as a heterodimer with β-2-Microglobulin and plays an important role in antigen presentation, specifically in the development and expansion of mucosal-associated invariant T cells (MAITs). MAITs are located in the gut and are involved in monitoring flora levels, as well as in conveying distress signals to other areas of the body, indicating a role for MR1 in proper digestion and immune system function组织相容性复合物相关蛋白MR1抗体. MR1 exists as four alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 1. Function: Similar to a typical class I MHC molecule, the MR1 (MHC-related 1) protein comprises a signal sequence, 3 extracellular 组织相容性复合物相关蛋白MR1抗体domains (alpha-1, alpha-2, and alpha-3), a transmembrane domain, and a cytoplasmic domain. MR1 encodes peptide-binding domains similar to those encoded by HLA class I genes. Gene ID: 3140 Database links: Entrez Gene: 3140 Human Omim: 600764 Human SwissProt: Q95460 Human Unigene: 101840 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组织相容性复合物相关蛋白MR1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid