髓鞘蛋白P0样蛋白3抗体
规格：1mg/1ml
英文名： MPZL3
别名： MPZL3; MPZL3_HUMAN; Myelin protein zero like 3; Myelin protein zero-like protein 3; PRO7425; UNQ2966.
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MPZL3
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞膜
髓鞘蛋白P0样蛋白3抗体产品介绍：background: MPZL3 is a 235 amino acid single-pass type I membrane protein that regulates homophilic cell-to-cell adhesion. A member of the myelin P0 protein family, MPZL3 contains one Ig-like V-type (immunoglobulin-like) domain and is expressed in brain, heart, liver and skin. The gene encoding MPZL3 maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary髓鞘蛋白P0样蛋白3抗体 angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. Function: Mediates homophilic cell-cell adhesion. Subcellular Location: Membrane. Similarity: Belongs to the myelin P0 protein family. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Gene ID: 196264 Database links: Entrez Gene: 521837 Cow Entrez Gene: 196264 Human Entrez Gene: 髓鞘蛋白P0样蛋白3抗体319742 Mouse Entrez Gene: 363054 Rat GenBank: BC113586 Human Omim: 611707 Human SwissProt: A5D7C3 Cow SwissProt: Q6UWV2 Human SwissProt: Q3V3F6 Mouse Unigene: 15396 Human Unigene: 49611 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
髓鞘蛋白P0样蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid