金属磷酸酯酶1抗体
规格：1mg/1ml
英文名： MPPE1
别名： Metallo phosphoesterase; Metallophosphoesterase 1; PGAP5; Post-GPI attachment to proteins factor 5
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MPPE1
交叉反应：Human, Mouse, Rat, Pig, Horse,
细胞定位：
金属磷酸酯酶1抗体产品介绍：background: Metallophosphoesterases (MPPEs) are dynamic enzymes that catalyze a variety of cellular reactions and contain a conserved beta-alpha-beta-alpha-beta fold. The MPPE superfamily is divided into two subfamilies: phosphomonoesterases and phosphodiesterases. Each MPPE has a dimetal center located approximately at the C-terminal end of the parallel ∫-strands of the fold. MPPE1 (Metallophosphoesterase 1) is a 396 amino acid multipass membrane enzyme that requires two divalent metals as cofactors. MPPE1 contains a N-terminal signal peptide, a typical metallophosphoesterase domain and a C-terminal transmembrane domain. Expression of MPPE1 seems to be limited to brain. There are five isoforms of MPPE1 that are produced as a result of alternative splicing events. Function:金属磷酸酯酶1抗体 The specific function of metallophosphoesterase 1 (MPPE1) is not yet known. There are 5 isoforms produced by alternative splicing which have molecular weights of 45 kDa, 39 kDa (2 isoforms), 38 kDa and 29 kDa. Subunit: Interacts with GPI-anchor proteins. Interacts with TMED10. Subcellular Location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein.金属磷酸酯酶1抗体 Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Note: Also localizes to endoplasmic reticulum exit site. Tissue Specificity: Expressed in brain. Similarity: Belongs to the metallophosphoesterase superfamily. MPPE1 family. Gene ID: 65258 Database links: Entrez Gene: 65258 Human Entrez Gene: 225651 Mouse Entrez Gene: 361344 Rat Omim: 611900 Human SwissProt: Q53F39 Human SwissProt: Q80XL7 Mouse SwissProt: B1WC86 Rat Unigene: 712666 Human Unigene: 235792 Mouse Unigene: 64185 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产金属磷酸酯酶1抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid