M期磷蛋白9抗体
规格:1mg/1ml
英文名: MPHOSPH9
别名: M phase phosphoprotein 9; M-phase phosphoprotein 9; Mphosph9; MPP 9; MPP9; MPP9_HUMAN.
分子量: 133kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MPHOSPH9
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆
M期磷蛋白9抗体产品介绍:background: Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase-promoting factor (MPF). In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M phase phosphoproteins (MPPs), also known as MPHOSPHs, permit disassembly of interphase structures and generation of M phase enzymatic activities and structures. MPP9 (M-phase phosphoprotein 9), also known as MPHOSPH9, is a 1,031 amino acid peripheral membrane protein of the Golgi apparatus that exists as two alternatively spliced isoforms.M期磷蛋白9抗体 The gene encoding MPP9 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p. Subcellular Location: Cytoplasm > cytoskeleton > centrosome > centriole. Golgi apparatus membrane.M期磷蛋白9抗体 Localizes to the distal and proximal end of centriole pairs in duplicated centrosomes. In ciliated cells, localizes to the distal and proximal end of daughter centriole and proximal of the mother centriole but not in the distal end of the mother centriole. Post-translational modifications: Phosphorylated in M (mitotic) phase. Gene ID: 10198 Database links: Entrez Gene: 10198 Human Omim: 605501 Human SwissProt: Q99550 Human Unigene: 577404 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
M期磷蛋白9抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid