Ran结合蛋白MOG1抗体
规格:1mg/1ml
英文名: MOG1
别名: DKFZp686F02139; homolog of yeast MOG1; HSPC165; HSPC236; likely ortholog of mouse RAN guanine nucleotide release factor; MGC110973; MOG 1; MOG1; MOG1 homolog; MOG1_HUMAN; RAN guanine nucleotide releas
分子量: 20kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human MOG1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核 细胞浆
Ran结合蛋白MOG1抗体产品介绍:background: This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] Function: May regulate the intracellular trafficking of RAN. In cardiac cells seems to regulate the cell surface localization of SCN5A. Subunit: Monomer (By similarity). Interacts with RAN, RAN-GTP and RAN-GDP.Ran结合蛋白MOG1抗体 Forms a complex with RAN-GTP and RANBP1 (By similarity). Interacts with the cytoplasmic loop 2 of SCN5A. Subcellular Location: Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm. Tissue Specificity: Isoform 1 and isoform 2 are ubiquitously Ran结合蛋白MOG1抗体expressed. Similarity: Belongs to the MOG1 family. Gene ID: 29098 Database links: Entrez Gene: 29098 Human Entrez Gene: 57785 Mouse Entrez Gene: 287419 Rat Omim: 607954 Human SwissProt: Q9HD47 Human SwissProt: Q9JIB0 Mouse Unigene: 408233 Human Unigene: 371612 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Ran结合蛋白MOG1抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 信号转导 结合蛋白 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid