磷酸化膜突蛋白抗体
规格:1mg/1ml
英文名: phospho-Moesin (Thr558)
别名: Moesin (phospho T558); p-Moesin (phospho T558); Membrane organizing extension spike protein; Membrane-organizing extension spike protein; MOES_HUMAN; Moesin; Moesin/anaplastic lymphoma kinase fusion p
分子量: 68kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthesised phosphopeptide derived from human
交叉反应:Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位:细胞浆 细胞膜
磷酸化膜突蛋白抗体产品介绍:background: Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008] Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. Subcellular Location: Cell membrane. Cytoplasm; cytoskeleton. Apical cell membrane. Cell projection; microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated磷酸化膜突蛋白抗体 forms seen after thrombin treatment. Tissue Specificity: In all tissues and cultured cells studied. Post-translational modifications: Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures. Similarity: Contains 1 FERM domain. Gene ID: 4478磷酸化膜突蛋白抗体 Database links: Entrez Gene: 4478 Human Entrez Gene: 17698 Mouse Omim: 309845 Human SwissProt: P26038 Human SwissProt: P26041 Mouse Unigene: 87752 Human Unigene: 138876 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化膜突蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid