线粒体类核因子1/乳腺癌相关蛋白SGA-81M抗体
规格：1mg/1ml
英文名： MNF1
别名： bA6B20.2; Breast cancer-associated protein SGA-81M; C6orf125; Cbp6; UQCC2_HUMAN; M19; Mitochondrial nucleoid factor 1; Mitochondrial protein M19; MNF1; RP11-6B20.2.
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MNF1
交叉反应：Human, Mouse, Rat, Cow, Horse, Sheep,
细胞定位：
线粒体类核因子1/乳腺癌相关蛋白SGA-81M抗体产品介绍：background: The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008] Function: Plays a role in the modulation of respiratory chain activities such as oxygen consumption 线粒体类核因子1/乳腺癌相关蛋白SGA-81M抗体and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Subcellular Location: Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space (By similarity). Mitochondrion matrix (By similarity). Mitochondrion inner membrane (By similarity).线粒体类核因子1/乳腺癌相关蛋白SGA-81M抗体 Note=Predominantly expressed in the mitochondrial inner membrane (By similarity). Tissue Specificity: Pancreas, skeletal muscle, kidney, liver and heart. Gene ID: 84300 Database links: Entrez Gene: 84300 Human Omim: 614461 Human SwissProt: Q9BRT2 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体类核因子1/乳腺癌相关蛋白SGA-81M抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 新陈代谢
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid