细胞外基质糖蛋白MMRN2抗体
规格：1mg/1ml
英文名： MMRN2
别名： Elastin microfibril interface located protein 3; Elastin microfibril interfacer 3; EMILIN-3; EndoGlyx-1 p125/p140 subunit; MMRN2; MMRN2_HUMAN; Multimerin-2.
分子量： 104kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MMRN2
交叉反应：Human, Mouse, Rat, Dog, Horse,
细胞定位：细胞外基质
细胞外基质糖蛋白MMRN2抗体产品介绍：background: This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012] Function: Inhibits endothelial cells motility and 细胞外基质糖蛋白MMRN2抗体acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA. Subunit: Heteromer of p110, p125, p140 and p200 subunits;disulfide-linked. Interacts with VEGFA. Subcellular Location: Secreted > extracellular space > extracellular matrix. Tissue Specificity: Endothelium. Post-translational modifications: N- and O-glycosylated. Similarity: Contains 1 C1q domain. Contains 1细胞外基质糖蛋白MMRN2抗体 EMI domain. Gene ID: 79812 Database links: Entrez Gene: 79812 Human Omim: 608925 Human SwissProt: Q9H8L6 Human Unigene: 524479 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞外基质糖蛋白MMRN2抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 糖蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid