滤泡树突细胞分泌蛋白抗体
规格:1mg/1ml
英文名: FDC-SP
别名: ADC; FDC; FDCs; FDC-SP; FDCSP; Follicular dendritic cell; Follicular dendritic cell secreted protein; Follicular dendritic cell; Follicular dendritic cell secreted peptide; FDC secreted protein.
分子量: 7.8kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FDC-SP
交叉反应:Human, Mouse, Rat, Horse,
细胞定位:分泌型蛋白
滤泡树突细胞分泌蛋白抗体产品介绍:background: Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow. In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes. Evidence in滤泡树突细胞分泌蛋白抗体 pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells. Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive滤泡树突细胞分泌蛋白抗体 activity on T cell stimulation. Subcellular Location: Secreted. Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. Gene ID: 260436 Database links: Entrez Gene: 260436 Human Omim: 607241 Human SwissProt: Q8NFU4 Human Unigene: 320147 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
滤泡树突细胞分泌蛋白抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid