血影蛋白β3/spectrin β IV抗体
规格：1mg/1ml
英文名： SPTBN3
别名： Spectrin beta chain, brain 3; Beta-IV spectrin; brain 3; KIAA1642; non-erythroid beta chain 3; QV; Spectrin; Spectrin beta chain; spectrin, beta, non-erythrocytic 4; spectrin, non-erythroid beta chain
分子量： 289kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SPTBN3
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
细胞定位：
血影蛋白β3/spectrin β IV抗体产品介绍：background: Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous Alpha and beta chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin beta IV is a non-erythrocytic member of the beta-spectrin family.血影蛋白β3/spectrin β IV抗体 It is expressed in brain and pancreatic islets and localizes to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Spectrin beta IV is a 2,564 amino acid protein with four isoforms due to alternative splicing events. Subcellular Location: Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Tissue Specificity: Abundantly expressed in brain and pancreatic islets. Similarity: Belongs to the spectrin family.血影蛋白β3/spectrin β IV抗体 Contains 2 CH (calponin-homology) domains. Contains 1 PH domain. Contains 18 spectrin repeats. Gene ID: 57731 Database links: Entrez Gene: 57731 Human Omim: 606214 Human SwissProt: Q9H254 Human Unigene: 32706 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血影蛋白β3/spectrin β IV抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid