血影蛋白抗体β5/spectrin β V抗体
规格：1mg/1ml
英文名： Spectrin beta 5
别名： Beta-V spectrin; brain 4; BSPECV; HUBSPECV; HUSPECV; non-erythroid beta chain 4; Spectrin; Spectrin beta chain; Spectrin beta chain, brain 4; Spectrin, non-erythroid beta chain 4; SPTBN4; SPTBN5; SPTN
分子量： 417kDa
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Spectrin
交叉反应：Human,
细胞定位：细胞浆
血影蛋白抗体β5/spectrin β V抗体产品介绍：background: Spectrin, an Actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous å and ∫ chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin ∫ V is a non-erythrocytic member of the ∫-spectrin family. It is expressed in brain and pancreatic islets and localizes to the cytoplasm of the cytoskeleton and cell cortex. Spectrin ∫ V is a 2,564 amino acid protein with 血影蛋白抗体β5/spectrin β V抗体four isoforms due to alternative splicing events. Subcellular Location: Cytoplasm > cytoskeleton. Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells. Tissue Specificity: Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, 血影蛋白抗体β5/spectrin β V抗体salivary gland, kidney, bladder, and heart. Similarity: Belongs to the spectrin family. Contains 2 CH (calponin-homology) domains. Contains 1 PH domain. Contains 31 spectrin repeats. Gene ID: 51322 Database links: Entrez Gene: 51332 Human Omim: 605916 Human SwissProt: Q9NRC6 Human Unigene: 709819 Human Unigene: 10100 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血影蛋白抗体β5/spectrin β V抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid