精子发生相关蛋白18抗体
规格：1mg/1ml
英文名： SPATA18
别名： 1700067I02Rik; FLJ32906; MGC93900; Mieap; mitochondria eating protein; SPATA18; Spermatogenesis associated 18; spermatogenesis associated 18 homolog (rat); Spermatogenesis associated protein 18; Sperm
分子量： 63kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SPATA18
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Chimpanzee, Macaque Monkey, Gorilla, Orangutan
细胞定位：细胞浆
精子发生相关蛋白18抗体产品介绍：background: SPATA18 is a 538 amino acid protein that is thought to play a role in cell differentiation during spermatogenesis, particularly during development from late elongate spematids to mature spermatozoa. Localizing to cytoplasm, SPATA18 is encoded by a gene that maps to human chromosome 4q12. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia,精子发生相关蛋白18抗体 Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: Potential role in spermatogenesis, especially in cell differentiation from late elongate spematids to mature spermatozoa. Subunit: Interacts (via coiled-coil domains) with BNIP3L (via BH3 domain). Interacts (via coiled-coil domains) with BNIP3 (via BH3 domain)精子发生相关蛋白18抗体. Subcellular Location: Cytoplasm. Similarity: Belongs to the MIEAP family. Gene ID: 132671 Database links: Entrez Gene: 132671 Human Entrez Gene: 289586 Rat Omim: 612814 Human SwissProt: Q8TC71 Human SwissProt: Q6AYL6 Rat Unigene: 527090 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
精子发生相关蛋白18抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid