精子发生相关蛋白20抗体
规格：1mg/1ml
英文名： SPATA20
别名： SPATA20; Sperm protein SSP411; Sperm-specific protein 411; Spermatogenesis associated 20; Spermatogenesis-associated protein 20; SPT20_HUMAN; Ssp411; Tisp78; Transcript increased in spermiogenesis 78.
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SPATA20
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Guinea Pig,
细胞定位：细胞外基质
精子发生相关蛋白20抗体产品介绍：background: SPATA20 is a 786 amino acid protein that may be involved in fertility regulation. SPATA20 is expressed in testis in an age dependent manner and localizes to round and elongated spermatids. SPATA20 contains a conserved thioredoxin-like domain near the N-terminus region and exists as four isoforms produced by alternative splicing events. SPATA20 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and精子发生相关蛋白20抗体 Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Function:精子发生相关蛋白20抗体 May play a role in fertility regulation. Subcellular Location: Secreted. Gene ID: 64847 Database links: Entrez Gene: 511363 Cow Entrez Gene: 491082 Dog Entrez Gene: 100714104 Guinea pig Entrez Gene: 100069987 Horse Entrez Gene: 64847 Human Entrez Gene: 217116 Mouse Entrez Gene: 100286812 Pig Entrez Gene: 360604 Rat Omim: 613939 Human SwissProt: Q8TB22 Human SwissProt: Q80YT5 Mouse SwissProt: Q6T393 Rat Unigene: 103147 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
精子发生相关蛋白20抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 干细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid