精子顶体膜相关蛋白1抗体
规格:1mg/1ml
英文名: SPACA1
别名: SACA1_HUMAN; SAMP32; SPACA1; Sperm acrosomal membrane-associated protein 32; Sperm acrosome membrane-associated protein 1.
分子量: 32kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SPACA1
交叉反应:Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep,
细胞定位:细胞膜
精子顶体膜相关蛋白1抗体产品介绍:background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the 精子顶体膜相关蛋白1抗体recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008] Function: May be involved in sperm-egg fusion. Subcellular Location: Membrane. Tissue Specificity: Testis specific. At the 精子顶体膜相关蛋白1抗体equatorial segment and the inner acrosomal membrane of capacitated sperm. Gene ID: 81833 Database links: Entrez Gene: 81833 Human Omim: 612739 Human SwissProt: Q9HBV2 Human Unigene: 161241 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
精子顶体膜相关蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 发育生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid