内皮素转化酶2抗体
规格：1mg/1ml
英文名： ECE2
别名： ECE2; MGC78487; ECE 2; Endothelin converting enzyme 2; Hypothetical protein MGC2408; KIAA0604; MGC17664; ECE2_HUMAN.
分子量： 80-100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ECE2
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 细胞膜
内皮素转化酶2抗体产品介绍：background: Endothelin-converting enzyme 2 (ECE2) converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity. Expressed at high levels in central nervous system. Expressed in adrenal glands, ovary and uterus, and at low levels in heart.内皮素转化酶2抗体 Subcellular Location: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity). Cytoplasmic granule membrane; Single-pass type II membrane protein (By similarity). Tissue Specificity: Expressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients (at protein level). Similarity: In the N-terminal section; belongs to the methyltransferase superfamily. In the C-terminal s内皮素转化酶2抗体ection; belongs to the peptidase M13 family. Gene ID: 9718 Database links: Entrez Gene: 281134 Cow Entrez Gene: 9718 Human Omim: 610145 Human SwissProt: Q10711 Cow SwissProt: O60344 Human Unigene: 146161 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
内皮素转化酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 神经生物学 转录调节因子 Alzheimer's
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid