人类组织相容性抗原HLA B7抗体
规格：1mg/1ml
英文名： HLA B7
别名： Abacavir hypersensitivity, susceptibility to; Drug-induced liver injury due to flucloxacillin; HLA B; HLA class I histocompatibility antigen B 7 alpha chain; HLA class I histocompatibility antigen, B-
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HLA B7
交叉反应：Human,
细胞定位：细胞膜
人类组织相容性抗原HLA B7抗体产品介绍：background: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008] Function: HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a 人类组织相容性抗原HLA B7抗体heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described. Subcellular Location: Cell Membrane, single pass type I membrane protein. Gene ID: 3106 Database links: Entrez Gene: 3106 Human Omim: 142830 Human SwissProt: P01889 Human SwissProt: P03989 Human SwissProt: P10319 Human SwissProt: P18463 Human SwissProt: P18464 Human SwissProt: P18465 Human SwissProt人类组织相容性抗原HLA B7抗体: P30460 Human SwissProt: P30461 Human SwissProt: P30462 Human SwissProt: P30464 Human SwissProt: P30466 Human SwissProt: P30475 Human SwissProt: P30479 Human SwissProt: P30480 Human SwissProt: P30481 Human SwissProt: P30483 Human SwissProt: P30484 Human SwissProt: P30485 Human SwissProt: P30486 Human SwissProt: P30487 Human SwissProt: P30488 Human SwissProt: P30490 Human SwissProt: P30491 Human SwissProt: P30492 Human SwissProt: P30493 Human SwissProt: P30495 Human SwissProt: P30498 Human SwissProt: P30685 Human SwissProt: Q04826 Human SwissProt: Q29718 Human SwissProt: Q29836 Human SwissProt: Q29940 Human SwissProt: Q31610 Human SwissProt: Q31612 Human SwissProt: Q95365 Human Unigene: 77961 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
人类组织相容性抗原HLA B7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid