OTOP2蛋白抗体
规格：1mg/1ml
英文名： OTOP2
别名： Otop2; OTOP2_HUMAN; Otopetrin-2.
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human OTOP2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
OTOP2蛋白抗体产品介绍：background: Otopetrins are multi-transmembrane domain proteins that share conserved gene and protein structure and are possibly involved in the formation of otoconia and otoliths. Located in the utricle and saccule of the inner ear, otoconia are complex calcium carbonate biominerals that are required for the normal sensation of gravity and linear acceleration. Vertigo and loss of balance may be attributed to degeneration of displacement of otoconia. The otopetrin family consists of three proteins, OTOP1, OTOP2 OTOP2蛋白抗体and OTOP3. These proteins have 12 putative transmembrane domains that are clustered into three otopetrin domains (OD-I, II and III). OTOP1 was the first described member of the Otopetrin family. Mutations of OTOP1 leads to absence of otoconia or otoliths, though inner ear development is normal. OTOP2 and OTOP3 share significant structural similarity with OTOP1 and may also play a role in the formation of mineralized structures. Subcellular Location: Membrane. Similarity: Belongs to the otopetrin family. Gene ID: 92736 Database links: Entrez Gene:OTOP2蛋白抗体 92736 Human Entrez Gene: 237987 Mouse Entrez Gene: 287820 Rat Omim: 607827 Human SwissProt: Q7RTS6 Human SwissProt: Q80SX5 Mouse Unigene: 352515 Human Unigene: 44542 Mouse Unigene: 218467 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
OTOP2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid